Human immunodeficiency virus is a sexually transmitted infection that does not have any cure till date. All the available treatment options for this disease are capable of suppressing the symptoms. Best among these treatment options is the one that suppresses AIDS-related symptoms for as long as possible. As per the recommendations made by a panel of leading AIDS specialists, highly active retroviral therapy or HAART is one such treatment option.

The basic objective of HAART method is to improve the life expectancy of a HIV-infected person by reducing the amount of virus present in the blood to very low or almost undetectable levels. This objective is achieved by means of administrating more than 2 different kinds of anti-retroviral drugs as a combination therapy. These anti-retroviral drugs are medications used for the treatment of infections caused by retroviruses like HIV. There are six different classes of antiretroviral drugs available in the market whose function is to act as potent inhibitors at different stages of HIV lifecycle and prevent the growth, replication and proliferation of the virus.

Combination of antiretroviral drugs belonging to different classes helps in creating multiple obstacles for the virus at each stage of its lifecycle thus reducing the ability of the virus to replicate. This strategy has also been effective against drug-resistant strains of HIV. Drug-resistant strains arise as a result of mutations occurring in the viral genome. The most favored combination of antiretroviral drugs in a HAART method is the triple-cocktail approach where two nucleoside-analogue RTIs and one non-nucleoside-analogue RTI or a protease inhibitor are used.

How HIV is Transmitted

The human immunodeficiency virus is chiefly caused by contact with vaginal fluid, semen or blood infected by the disease. HIV is typically spread via these three causes:

- HIV may be spread to infants from their mothers during childbirth or during nursing.
- Sexual contact with someone infected with HIV.
- Contact with an infected needle or syringe (Sharing needles with someone infected with HIV).

HIV Precautionary Measures Include:

- Discuss HIV and other STDs with your sexual partner.
- Learn as much as possible about your partner’s past sexual behavior, other sexual partners, drug use and lifestyle.
- Use a condom every time you have sexual intercourse.
- Never share needles or syringes with anyone.
- Get tested for HIV and other STDs.

HIV Treatments

Although there is no known cure for HIV/AIDS, it is a manageable virus. Advances in HIV treatments since the HIV/AIDS epidemic began in the 1980s have helped to weaken the progression of the HIV infection to AIDS. As a result of advancements in medical research and sciences, the number of fatalities resulting from AIDS has decreased in the United States. All blood donated to blood banks and infirmaries in the United States are now tested for HIV. As a result, contracting HIV from a blood transfusion is very rare.According to the National Institute of Allergy and Infectious Diseases, there are currently thirty-one antiretroviral drugs (ARVs) approved by the U.S. Food and Drug Administration for the treatment of HIV and AIDS. These drugs do not cure or get rid of HIV or AIDS, but they do suppress the virus and allow the infected person to live a longer, richer, healthier life. It is important to note, that although the virus can be suppressed via use of ARVs, HIV/AIDS can still be spread by the infected individual. It is important that the infected person use all precautions to forestall the spread of the virus to others.

Treatment Complications, Risks and Possible Side Effects

Like many drug treatments, the medications used to treat HIV/AIDS can cause complications and side effects. Antiretroviral drugs (ARVs) on rare occasion can cause serious medical complications including: changes in metabolism and bone loss. Patients need to be aware of possible complications when taking any medication and be alert to their body’s response to the drug. It is important to communicate any concerns regarding your HIV treatment with your physician.

Research has shown that HIV can create strains resistant to antiretroviral drugs when patients fail to take all their prescribed medications consistently. It is essential for patients to talk to their physicians regarding their concerns or hardships with their suggested drug regimens. Some patients experience disagreeable side effects and may have difficulty keeping up with the required daily medication schedule. If this is the case, it is recommended that the patient and physician find an alternative solution as quickly as possible as inconsistency with antiretroviral drugs may allow the HIV infection to become resistant to that specific treatment.

HIV Support Groups

Support groups and connections with others who are also living with HIV/AIDS may provide some benefit. Connecting with others who share your medical condition may provide emotional support, a sense of unity and may help prevent individuals from feeling isolated in their illness. The

World Health Organization states that support groups can provide important psychosocial support to individuals living with HIV/AIDS. Becoming infected with HIV can affect all aspects of the infected individual’s life as well as the life of their family and caregivers. Support groups may help HIV patients better cope with their illness. Support groups should not be used to replace professional psychological services.

Causes of HIV

The spread of HIV inside the body is in such a way that the virus splits the inherent cryptogram of the cells which are utilised by the immune system, especially cells called ‘CD4 cells’ and further utilizes the natural inherent matter in order to create replicas of itself. The body is able to create more of the’CD4′ cells, but sooner or later the virus HIV would bring down the number of the ‘CD4′ cells to a very low level which in turn would end up in stopping the functioning of the immune system.

The spreading of the virus HIV outside the system is due to transmission of fluids from the body, like blood or semen. Thus this virus could be transmitted due to sexual intercourse, which would include even anal and oral sex. The risk of the transmission of HIV is there also in case of the sharing of needles while injecting illegal drugs. HIV can also be transmitted by the mother to the baby. But nowadays there are medications available wherein the possibility can be brought down. HIV is also transmitted by blood transfusions.

Symptoms of HIV

The first stage of the infection is called the ‘primary HIV infection’. The persons infected by this virus, about more than half of the people develop the symptoms, generally in about 15 to 45 days of the infection. The symptoms would comprise of pain in the joints, fever, muscle pain, sore throat, and swelling in the glands, getting tired out faster than usual and appearance of a spotty rash on the chest. Generally the symptoms are quite mild and you would tend to link them to some other problem like fever or cold. These symptoms do not show any increment for a long period. This is called ‘Asymptomatic HIV infection’.

This virus is internally growing and even damaging the immune system. If the virus is left and not treated, it in turn will bring down the number of the CD4 cells in the body to a very low level and this would cause the immune system to stop functioning. This damage caused to the immune system generally happening in over a period of ten years. This in turn would inexorably result in growing into a severe infection. The symptoms of a severe infection would be, night sweats, dry cough, inexplicable loss of weight, high fever which would be enduringly long, vision would start getting blur, the mouth or the tongue would develop white spots, shortness in breath, constant diarrhea or even glands tend to swell up and this condition would continue for three or more months.

Treatment of HIV

The first step would be getting referred to a HIV clinic and getting counseled. Then blood tests would be done regularly, these tests would be to keep a check on the viral load and the CD4 cell count. There is no vaccine or medication available which can cure HIV completely. But there are medications like HAART available in order to slow down the speed of the virus and also giving you a longer life span. There are also various therapies done alone and also in combination with medication to give the sufferer a better life.

Around the world, women now make up half of all people living with HIV, the human immunodeficiency virus, and AIDS, acquired immunodeficiency syndrome. In the U.S., more than 25 percent of new infections are in women. Women of color are especially impacted by the disease. HIV/AIDS is the leading cause of death for African American women aged 25 to 34. Although most of the cases reported early in the epidemic were men, it was not long before AIDS in women was identified. Women contracted the disease primarily by sex with bisexual men or infected drug-using men or through sharing contaminated needles with infected injection drug users. The proportion of all AIDS cases that were women and adolescent girls increased from 8% in 1986 to 26% in 2001. The first symptoms of HIV infection are very much the same in men and women, although they may be more pronounced in women. They are similar to those of other acute viral illnesses: fever, joint pain, muscle ache, diarrhea, vomiting and lymphadenopathy. Weight loss, sore throat, rash and oral ulcers are also common.

Women also experience HIV-associated gynecologic problems, many of which occur in uninfected women but with less frequency or severity. Vaginal yeast infections, common and easily treated in most women, often are particularly persistent and difficult to treat in HIV-infected women. Other vaginal infections may occur more frequently and with greater severity in HIV-infected women, including bacterial vaginosis and common STIs such as gonorrhea, chlamydia, and trichomoniasis.

Severe herpes simplex virus ulcerations, which are sometimes unresponsive to therapy with the standard drug acyclovir, can severely compromise a woman’s quality of life. Idiopathic genital ulcers, with no evidence of an infectious organism or cancerous cells in the lesion, are a unique manifestation of HIV infection. HPV infections, which cause genital warts and can lead to cervical cancer, occur more frequently in HIV-infected women. A precancerous condition associated with HPV, called cervical dysplasia, is also more common and more severe in HIV-infected women and more apt to recur after treatment. PID appears to be more common and more aggressive in HIV-infected women than in uninfected women. Menstrual irregularities frequently are reported by HIV-infected women too.

Women whose HIV infections are detected early and receive appropriate treatment survive as long as HIV-infected men. Although several studies have shown HIV-infected women to have shorter survival times than men, this may be because women are less likely than men to be diagnosed early. In an analysis of several studies involving more than 4,500 people with HIV infection, women were 33 percent more likely than men to die within the study period. The investigators could not definitively identify the reasons for excess mortality among women in this study, but they speculated that poorer access to or use of health care resources among HIV-infected women as compared to men, domestic violence, homelessness, and lack of social supports may have been important factors.

Merck & Co., a drug manufacturer in New Jersey, conducted clinical trials on a new pill. It is to be taken orally twice per day to help slow the progression of the disease. Studies indicated this drug is performing better than the other medications currently on the market. This drug will be especially beneficial to long term AIDS sufferers who have developed a resistance to pharmaceuticals existing today.

The studies were performed on 167 patients who have shown progression of the disease and have critically impaired health. Many of these patients have taken the drug AZT, a common treatment, for more than ten years. In the clinical trials, varying doses of the drug were experimented on with patients with varying conditions. In the most successful group, seventy two percent of the patients showed an improvement with virus levels becoming undetectable. In the least successful group, virus levels were reduced to undetectable amounts in fifty six percent. The results of the clinical trial were surprising but welcomed. The effects were astounding and the drug manufacturer is hopeful that it will help prolong the lives of people with AIDS. They are continuing to conduct research in larger trials and hope to apply for approval from the Food and Drug Administration in 2007.

Gilead Sciences, a competing drug manufacturer, also showed positive results from a similar type drug. Although the clinical trials were much smaller then Merck’s, the company is hopeful the results will set the stage for larger trials. The drug is called an integrase inhibitor. Integrase is an enzyme that speeds the progression of HIV. The inhibitor blocks the enzyme, slowing this process. The initial trials were only conducted with only ten patients. However, after ten days there was a one hundred fold reduction in virus levels. Similar to the Merck study, this shows promise in helping to prolong the life of patients. This pill will be taken once per day in conjunction with Novir, another AIDS medication. Increased studies of this drug will begin in the spring of 2006.

Acquired Immune Deficiency syndrome or AIDS is a collection of symptoms and infections resulting from the specific damage to the immune system caused by the human immunodeficiency virus. The late stage of the condition leaves individuals prone to opportunistic infections and tumors. Although treatments for AIDS and HIV exist to slow the virus’s progression, but, there is no known cure. There is currently no vaccine or cure for HIV or AIDS. The only known method of prevention are based on avoiding exposure to the virus or failing that an antiretroviral treatment directly after a highly significant exposure, called post-exposure prophylaxis.

Well current treatment for HIV infection consists of highly active antiretroviral therapy, also known as HAART. HAART allows the stabilization of the patient’s symptoms and viremia, but it neither cures the patient of HIV, nor alleviates the symptoms, and high levels of HIV-1, often HAART resistant, return once treatment is stopped. Moreover, it would take more than the lifetime of an individual to be cleared of HIV infection using HAART. Despite this, many HIV-infected individuals have experienced remarkable improvements in their general health and quality of life, which has led to the plummeting of HIV-associated morbidity and mortality. In the absence of HAART, progression from HIV infection to AIDS occurs at a median of between nine to ten years and the median survival time after developing AIDS is only 9.2 months. HAART is thought to increase survival time by between 4 and 12 years. This average reflects the fact that for some patients and in many clinical cohorts this may be more than fifty percent of patients HAART achieves far less than optimal results. This is due to a variety of reasons such as medication intolerance/side effects, prior ineffective antiretroviral therapy and infection with a drug-resistant strain of HIV.

Now AIDS is curable!!!

Now AIDS is completely curable. Though it is unbelievable it is true. Siddha medical system is one of the familiar ancient medical systems of India challenging to cure the terrible disease AIDS. Based on the Siddha medical system so many traditional medical practitioners of Tamilnadu, India were being tried to identify the suitable potential drug to cure AIDS.

But Dr. S.K. Balasubramaniam, Traditional Siddha Medical Practitioner in Erode, Tamilnadu, India was invented a drug namely VAIROLINN which is extracted from some rare herbals. It is highly potential to cure AIDS 100% without any residue. Vairolinn has already passed various studies such  1) Animal Study  2) Pathological study  3) Cell to cell Study etc., which resulted that  the Herbal Medicine “Vairolinn” has no side effect and no toxic substances found included Steroids. 

From the beginning about 120 HIV affected patients were being treated with our drug Vairolinn.  Most of the patients were completely recovered from this terrible disease within Six months of treatment Period.  Only few of them need up to nine months of treatment to recover completely depending upon their HIV Viral Load.

For example, one patient namely Mr. V. Sunderajan, Age 32 (in 1999) Male having HIV Viral load initially about 2, 70,000 copies/ml has taken our Herbal medicine Vairolinn regularly. After 70 days of treatment his viral load decreased into 1, 05,000 copies/ml (as 03.08.1999, 61.11% improvement) and subsequently decreased in to 506 copies/ml (99.81% Improvement) after 160 days of treatment and continued our treatment up to 200 days. The patient is still alive in good Health Condition.  After the completion of Eight year Mr. V. Sunderajan was subjected to follow up analysis, an unbelievable and ever achieved result as “HIV Viral load could not be ascertained” obtained.  It simply conformed that our Herbal Medicine is completely cure the HIV/AIDS without any residue.

Though it is a great achievement, we could not able to market the said medicine directly due lack of financial background.  Therefore we decide to sell the product with complete technical details or to market the medicine with the collaboration of others who have sufficient marketing potential.

Test reports of few patients and reports of various studied already involved are also published in our website www.crpharmaa.com . Kindly visit our website to go through the reports.

If you have any idea to market our product, kindly contact us. We are always ready to clarify your doubts if any raised and also ready to prove the efficiency of drug Vairolinn.

Please fell free to contact “ crpharmaa@gmail.com “ to clarify your doubts.